The aim of this study was to compare next-generation sequencing (NGS) with the traditional fluorescence in situ hybridization (FISH) for detecting segmental chromosomal aberrations (SCAs) such as 1p deletion, 11q deletion and 17q gain, which are well-known predictive markers for adverse outcome body surf board in neuroblastoma.The tumor tissue obta
Abstract Background The rapid adoption of CRISPR technology has enabled biomedical researchers to conduct CRISPR-based genetic screens in a pooled format.The quality of results from such screens is heavily dependent on the selection of optimal screen design parameters, which also affects cost and scalability.However, the cost and effort of implemen
Space flights, some physical activities, and extreme sports can greatly alter the gravitational forces experienced by the body.Being a deviation from the constant pull of Earth, these alterations can be considered gravitational stress and have the potential Safety Locks to affect physiological processes.Physical cues play a vital role in the homeos